SPRS-therapy (Service for Personal Regeneration of Skin)

In December 2010 HSCI brought to the market SPRS-therapy – a comprehensive set of services for individual skin regeneration based on a new technology of applying autologous dermal fibroblasts to correct the effects of aging and skin defects.

The technology of using autologous demal fibroblasts for skin defects treatment, used in the SPRS-therapy service, was approved by the Russian healthcare regulator (Roszdravnadzor) in 2009.

The SPRS-therapy service is provided via health clinics. Today the service is offered at the leading dermatology and cosmetics clinics of Moscow and the Company is making steps for entering regional markets.

SPRS-therapy is a complex of personalized diagnostics and treatment procedures for repairing skin damage due to aging or other structural changes.

The service includes:

• diagnostics of the condition of the patient’s skin;
• a therapy course using the cell product with the patient’s own fibroblasts;
• and long-term storage of the patient’s skin fibroblast culture in cryogenic bank.

 

Creation of the SPRS-bank — the patient’s own dermal fibroblasts
After being isolated from fragments of skin taken from behind the patient’s ear, the fibroblasts are cultivated in laboratory conditions using special techniques for 6-7 weeks. A sample of cell material from each patient undergoes compulsory safety testing in order to eliminate the risk of contamination.

Cryopreservation of the SPRS-bank
Individual SPRS-banks are placed in a cryostorage, where they can be preserved in liquid nitrogen for an unlimited length of time and used throughout the patient’s lifetime.

SPRS-product — a suspension of the patient’s own cultivated fibroblasts
The minimum appropriate quantity of fibroblasts is taken from the SPRS-bank to develop the needed dose of the cell product to be administered intradermally.

SPRS-therapy is based on dosed impregnation of the patient’s skin within the areas of concern with the patient’s own skin cells (autologous dermal fibroblasts). The fibroblasts then synthesize collagen, elastin, hyaluronic acid and other important elements of the extracellular matrix therefore restoring the physiological balance in the skin and the natural renewal processes of the dermis. The therapy reduces the number and depth of wrinkles, improves the skin surface, thickens the derma and increases its collagen density.

SPRS-diagnostics — studying the patients skin fibroblasts.
The patient’s skin is studied with the help of modern laboratory methods allowing for an assessment of the quantity and functional activity of existing fibroblasts in the skin as well as their ability to divide, which makes possible to evaluate the regenerative and proliferative potential of the fibroblast population in the skin of each individual patient.